Home > iHuman Institute > Faculty > Kurt Wüthrich
Kurt Wüthrich    Distinguished Adjunct Professor
Institute iHuman Institute
Research Area structural biology
Contact Info. wuthrich@@scripps.edu
 
  Biography  
1957–62 University of Bern, Switzerland: Lizentiat in chemistry, physics and mathematics. 1962–64 University of Basel, Switzerland: Ph.D. in chemistry (Prof. S. Fallab); Eidgen?ssisches Turnund Sportlehrerdiplom. 1964–65 University of Basel, Switzerland: Postdoctoral training (Prof. S. Fallab). 1965–67 University of California, Berkeley, CA, USA : Postdoctoral training (Prof. R.E. Connick). 1967–69 Bell Telephone Laboratories, Murray Hill, N.J., USA : Member Technical Staff, Biophysics Department (Dr. R.G. Shulman). 1969– ETH Zurich, Zurich, Switzerland: Privatdozent (70), Assistant Professor (72), Associate Professor (76), Professor of Biophysics (80); Chairman Biology Department (95–2000). 2001–04 The Scripps Research Institute, La Jolla, CA, USA: Cecil H. and Ida M. Green Visiting Professor of Structural Biology. 2004– The Scripps Research Institute, La Jolla, CA, USA: Cecil H. and Ida M. Green Professor of Structural Biology.
  Research Interests  
Biology, structure and function of proteins and nucleic acids; development of nuclear magnetic resonance (NMR) techniques for macromolecular structure determination in solution and for studies of intermolecular interactions; applications in structural genomics, proteomics and biomedical research.
  Selected Publications  
1.Liu, J.J., Horst, R., Katritch, V., Stevens, R.C. and Wüthrich, K. (2012) Biased signaling pathways in β2-adrenergic receptor characterized by 19F-NMR. Science 335, 1106-1110.
2.Horst, R., Stanczak, P., Serrano, P. and Wüthrich, K. (2012) Translational diffusion measurements by microcoil NMR in aqueous solutions of the Fos-10 detergent-solublized membrane protein OmpX. J. Phys. Chem. B 116, 6775–6780.
3.Serrano, P., Pedrini, B., Mohanty, B., Geralt, M., Herrmann, T. and Wüthrich K. (2012) The J-UNIO protocol for automated protein structure determination by NMR in solution. J. Biomol. NMR 53, 341–354.
4.Stanczak, P., Zhang, Q., Horst, R., Serrano, P. and Wüthrich, K. (2012) Micro-coil NMR to monitor optimization of the reconstitution conditions for the integral membrane protein OmpW in detergent micelles. J. Biomol. NMR 54, 129–133.
5.Horst, R., Stanczak, P., Stevens, R.C. and Wüthrich, K. (2012) β2-adrenergic receptor solutions for structural biology analyzed with micro-scale NMR diffusion measurements. Angew. Chem. 52(1):331-335.
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