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赵国屏    特聘教授
所在学院 生命科学与技术学院
中科院上海生命科学研究院植物生理生态研究所
研究方向 微生物基因组学与分子生理学(中科院上海生命科学研究院植物生理生态研究所研究员)
联系方式 gpzhao@@sibs.ac.cn
备注 中国科学院院士
 
  主要研究内容  
1. 微生物分子生理(病理):利用比较基因组和功能基因组技术研究微生物致病机理与致病基因,研究工业微生物、特别是乳酸菌与放线菌的生理与代谢过程的调控规律及其改造和利用。 2. 合成生物学:探索建立系统合成生物学的工作原理(如定量生物学和正交生物学原理)及使能技术体系并开发其在生物技术产业中应用的潜力。 3. 人类健康与疾病基因组研究。
  代表性论文  
1. WANG, Qijun, Yakun Zhang, Chen Yang, Hui Xiong, Yan Lin, Jun Yao, Hong Li, Lu Xie, Wei Zhao, Yufeng Yao, Zhibin Ning, Rong Zeng, Yue Xiong, Kunliang Guan, Shimin Zhao*, Guoping Zhao* (2010) Acetylation of Metabolic Enzymes Coordinates Carbon Source Utilization and Metabolic Flux. Science 327: 1004-1007.
2. Wei Zhao, Yi Zhong, Hua Yuan, Jin Wang, Huajun Zheng, Ying Wang, Xufeng Cen, Feng Xu, Jie Bai, Xiaobiao Han, Gang Lu, Yongqiang Zhu, Zhihui Shao, Han Yan, Chen Li, Nanqiu Peng, Zilong Zhang, Yunyi Zhang, Wei Lin, Yun Fan, Zhongjun Qin, Yongfei Hu, Baoli Zhu, Shengyue Wang*, Xiaoming Ding* and Guo-Ping Zhao* (2010) Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism. Cell Res 20: 1096–1108.
3. Liangdong Lu, Qing Sun, Xiao-yong Fan, Yi Zhong, Yu-feng Yao*, Guo-Ping Zhao* (2010) Mycobacterial MazG is a novel NTP pyrophosphohydrolase involved in oxidative stress response. J Biol Chem 285: 28076-85.
4. Ying Wang, Xu-Feng Cen, Guo-Ping Zhao* and Jin Wang* (2012) Characterization of a new GlnR binding box in the promoter of amtB in Streptomyces coelicolor inferred a PhoP/GlnR competitive binding mechanism for transcriptional regulation of amtB. J Bacteriol 194: 5237-5244.
5. Ke Wang, Rong Zhang, Xiaohui Xiang, Fei He, Libo Lin, Xingjie Ping, Lei Yu, Jisheng Han, Guoping Zhao*, Qinghua Zhang*, Cailian Cui* (2012) Differences in neural-immune gene expression response in rat spinal dorsal horn correlates with variations in electroacupuncture analgesia. PLoS ONE 7: e42331.
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